| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MLLT10 (250-500) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MLLT10 |
| Gene ID: |
8028 |
| Uniprot ID: |
AF10_HUMAN |
| Immunogen Region: |
250-500 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human MLLT10 (NP_001182555.1). |
| Immunogen Sequence: |
EPSPALVPSLTVTTEKTYTS TSNNSISGSLKRLEDTTARF TNANFQEVSAHTSSGKDVSE TRGSEGKGKKSSAHSSGQRG RKPGGGRNPGTTVSAASPFP QGSFSGTPGSVKSSSGSSVQ SPQDFLSFTDSDLRNDSYSH SQQSSATKDVHKGESGSQEG GVNSFSTLIGLPSTSAVTSQ PKSFENSPGDLGNSSLPTAG YKRAQTSGIEEETVKEKKRK GNKQSKHGPGRPKGNKNQE |
| Tissue Specificity | Expressed abundantly in testis. |
| Function | Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation. |
| Protein Name | Protein Af-10All1-Fused Gene From Chromosome 10 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Af-10 antibodyAnti-All1-Fused Gene From Chromosome 10 Protein antibodyAnti-MLLT10 antibodyAnti-AF10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
