• Western blot analysis of various lysates using CNTRL Rabbit polyclonal antibody (STJ117332) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.

Anti-CNTRL antibody (250-500) (STJ117332)

SKU:
STJ117332

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CNTRL (250-500) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTRL
Gene ID: 11064
Uniprot ID: CNTRL_HUMAN
Immunogen Region: 250-500
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-500 of human CNTRL (NP_008949.4).
Immunogen Sequence: LEGQPVTTQDRQEAFERFSL EEVERLERDLEKKMIETEEL KSKQTRFLEEIKNQDKLNKS LKEEAMLQKQSCEELKSDLN TKNELLKQKTIELTRACQKQ YELEQELAFYKIDAKFEPLN YYPSEYAEIDKAPDESPYIG KSRYKRNMFATESYIIDSAQ AVQIKKMEPDEQLRNDHMNL RGHTPLDTQLEDKEKKISAA QTRLSELHDEIEKAEQQILR ATEEFKQLEEAIQLKKISE
Tissue Specificity Widely expressed with highest levels in testis and trachea.
Function Involved in cell cycle progression and cytokinesis. During the late steps of cytokinesis, anchors exocyst and SNARE complexes at the midbody, thereby allowing secretory vesicle-mediated abscission.
Protein Name Centriolin
Centrosomal Protein 1
Centrosomal Protein Of 110 Kda
Cep110
Database Links Reactome: R-HSA-1839117 Q7Z7A1-3
Reactome: R-HSA-2565942
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-5655302 Q7Z7A1-3
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Midbody
Midbody Ring
Alternative Antibody Names Anti-Centriolin antibody
Anti-Centrosomal Protein 1 antibody
Anti-Centrosomal Protein Of 110 Kda antibody
Anti-Cep110 antibody
Anti-CNTRL antibody
Anti-CEP1 antibody
Anti-CEP110 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance