| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MAPKBP1 (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MAPKBP1 |
| Gene ID: |
23005 |
| Uniprot ID: |
MABP1_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPKBP1 (NP_001122080.1). |
| Immunogen Sequence: |
MAVEGSTITSRIKNLLRSPS IKLRRSKAGNRREDLSSKVT LEKVLGITVSGGRGLACDPR SGLVAYPAGCVVVLFNPRKH KQHHILNSSRKTITALAFSP |
| Tissue Specificity | Expressed in intestinal mucosa, where it is detected in epithelial cells, endothelial cells, smooth muscle cells and immune cells, such as lymphocytes. Expressed in kidney. |
| Function | Negative regulator of NOD2 function. It down-regulates NOD2-induced processes such as activation of NF-kappa-B signaling, IL8 secretion and antibacterial response. Involved in JNK signaling pathway. |
| Protein Name | Mitogen-Activated Protein Kinase-Binding Protein 1Jnk-Binding Protein 1Jnkbp-1 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonSpindle PoleNot Detected In The CiliumLocalized Around The Poles Of The Mitotic Spindle From Prophase To Anaphase In Mitotic Cells |
| Alternative Antibody Names | Anti-Mitogen-Activated Protein Kinase-Binding Protein 1 antibodyAnti-Jnk-Binding Protein 1 antibodyAnti-Jnkbp-1 antibodyAnti-MAPKBP1 antibodyAnti-JNKBP1 antibodyAnti-KIAA0596 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
