Anti-Lck-interacting molecule [LIME] antibody (STJ16101298)

Anti-Lck-interacting molecule [LIME] antibody (STJ16101298)

SKU:
STJ16101298-01
$725.63
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Lck-interacting molecule [LIME] is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Formulation: Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification: Affinity purified
Concentration: 1 mg/mL
Storage Instruction: Store at 2-8°C upon receipt.
Immunogen: Bacterially expressed intracellular fragment corresponding to aa 141-295 of human LIME.
Background LIME (Lck-interacting molecule) is a 30 kDa double-palmitoylated protein with unusually basic cytoplasmic domain, expressed by T cells. After ligation of CD4 or CD8 T cell coreceptors, LIME is phosphorylated by Src-family kinases and associates with Lck and Fyn kinases and with their negative regulator Csk. Interestingly, Csk-mediated phosphorylation of C-terminal negative-regulatory tyrosine of LIME-associated Lck can result in increase of enzymatic activity compared with the total pool of Lck, thus, LIME serves as a positive regulator of TCR-dependent T cell signaling. However, under some circumstances, LIME may mediate inhibitory signals.

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ16100293 Anti-Lck-interacting molecule antibody [LIME-10] (STJ16100293) Mouse Monoclonal Human WB/IHC-P
STJ16100292 Anti-Lck-interacting molecule antibody [LIME-06] (STJ16100292) Mouse Monoclonal Human IP/FC
STJ98215 Anti-LCK antibody [8E5F9/4B2C7] (STJ98215) Mouse Monoclonal Human WB/ELISA
STJ22226 Anti-Phospho-LCK-Y394 antibody (STJ22226) Rabbit Polyclonal Human/Mouse WB/IF/ICC/ELISA
STJ501585 Anti-LCK antibody (500-539) (STJ501585) Rabbit Polyclonal Human/Mouse/Rat ELISA/IP/WB
STJ24379 Anti-LCK antibody (1-240) (STJ24379) Rabbit Polyclonal Human/Mouse/Rat WB/IHC-P/ELISA
STJ72745 Anti-LCK antibody (39-52) (STJ72745) Goat Polyclonal Human/Mouse/Rat/Dog/Pig/Cow Pep-ELISA/WB
STJ22227 Anti-Phospho-LCK-Y505 antibody (STJ22227) Rabbit Polyclonal Human WB/IP/ELISA
STJ501586 Anti-LCK antibody (500-539) {Biotin} (STJ501586) Rabbit Polyclonal Human/Mouse/Rat ELISA/IP/WB
!