| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-Inositol 1-4-5-Trisphosphate Receptor Type 3 is suitable for use in Western Blot research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S5047RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:2000-1:6000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ITPR3 |
| Gene ID: | 3710 |
| Uniprot ID: | ITPR3_HUMAN |
| Immunogen: | Recombinant protein of human ITPR3. |
| Tissue Specificity | Expressed in intestinal crypt and villus epithelial cells. |
| Post Translational Modifications | Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues. |
| Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. Involved in cellular calcium ion homeostasis. |
| Protein Name | Inositol 1 -4 -5-Trisphosphate Receptor Type 3Ip3 Receptor Isoform 3Ip3r 3Insp3r3Type 3 Inositol 1 -4 -5-Trisphosphate ReceptorType 3 Insp3 Receptor |
| Database Links | Reactome: R-HSA-112043Reactome: R-HSA-114508Reactome: R-HSA-139853Reactome: R-HSA-1489509Reactome: R-HSA-2029485Reactome: R-HSA-2871809Reactome: R-HSA-381676Reactome: R-HSA-4086398Reactome: R-HSA-422356Reactome: R-HSA-5218921Reactome: R-HSA-5578775Reactome: R-HSA-5607763Reactome: R-HSA-9664323Reactome: R-HSA-9717207Reactome: R-HSA-983695 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Inositol 1 -4 -5-Trisphosphate Receptor Type 3 antibodyAnti-Ip3 Receptor Isoform 3 antibodyAnti-Ip3r 3 antibodyAnti-Insp3r3 antibodyAnti-Type 3 Inositol 1 -4 -5-Trisphosphate Receptor antibodyAnti-Type 3 Insp3 Receptor antibodyAnti-ITPR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
