• Western blot analysis of the lysates from HeLa cells using HEXIM1 antibody.
  • Immunofluorescence analysis of HeLa cells, using HEXIM1 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from NIH/3T3 cells, using HEXIM1 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of RAT-HEART cells using Hexim1 Polyclonal Antibody diluted at 1：2000

Anti-HEXIM1 antibody (181-230 aa) (STJ93494)

SKU:
STJ93494

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein HEXIM1 (181-230 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HEXIM1
Gene ID: 10614
Uniprot ID: HEXI1_HUMAN
Immunogen Region: 181-230 aa
Specificity: Hexim1 Polyclonal Antibody detects endogenous levels of Hexim1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human HEXIM1 at the amino acid range 181-230
Function Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
Protein Name Protein Hexim1
Cardiac Lineage Protein 1
Estrogen Down-Regulated Gene 1 Protein
Hexamethylene Bis-Acetamide-Inducible Protein 1
Menage A Quatre Protein 1
Cellular Localisation Nucleus
Cytoplasm
Binds Alpha-Importin And Is Mostly Nuclear
Alternative Antibody Names Anti-Protein Hexim1 antibody
Anti-Cardiac Lineage Protein 1 antibody
Anti-Estrogen Down-Regulated Gene 1 Protein antibody
Anti-Hexamethylene Bis-Acetamide-Inducible Protein 1 antibody
Anti-Menage A Quatre Protein 1 antibody
Anti-HEXIM1 antibody
Anti-CLP1 antibody
Anti-EDG1 antibody
Anti-HIS1 antibody
Anti-MAQ1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance