Anti-HAS3 antibody (STJA0007163)

SKU:
STJA0007163
$64.80 - $340.20
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Hyaluronan synthase 3 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HAS3
Gene ID: 3038
Uniprot ID: HYAS3_HUMAN
Specificity: This antibody detects endogenous levels of HAS3 at Human, Mouse
Immunogen: Synthesized peptide derived from human HAS3
Function Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis.
Protein Name Hyaluronan Synthase 3
Hyaluronate Synthase 3
Hyaluronic Acid Synthase 3
Ha Synthase 3
Database Links Reactome: R-HSA-2142850
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Golgi Apparatus
Trans-Golgi Network Membrane
Early Endosome
Travels From Endoplasmic Reticulum (Er)
Golgi To Plasma Membrane
Actives Only When Present In Plasma Membrane
O-Glcnacylation Controls Its Membrane Localization
A Rapid Recycling Of Has3 Between Plasma Membrane And Endosomes Is Controlled By The Cytosolic Levels Of Udp-Glcua And Udp-Glcnac
Alternative Antibody Names Anti-Hyaluronan Synthase 3 antibody
Anti-Hyaluronate Synthase 3 antibody
Anti-Hyaluronic Acid Synthase 3 antibody
Anti-Ha Synthase 3 antibody
Anti-HAS3 antibody

Information sourced from Uniprot.org

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