| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hyaluronan synthase 3 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HAS3 |
| Gene ID: |
3038 |
| Uniprot ID: |
HYAS3_HUMAN |
| Specificity: |
This antibody detects endogenous levels of HAS3 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human HAS3 |
| Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis. |
| Protein Name | Hyaluronan Synthase 3Hyaluronate Synthase 3Hyaluronic Acid Synthase 3Ha Synthase 3 |
| Database Links | Reactome: R-HSA-2142850 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneGolgi ApparatusTrans-Golgi Network MembraneEarly EndosomeTravels From Endoplasmic Reticulum (Er)Golgi To Plasma MembraneActives Only When Present In Plasma MembraneO-Glcnacylation Controls Its Membrane LocalizationA Rapid Recycling Of Has3 Between Plasma Membrane And Endosomes Is Controlled By The Cytosolic Levels Of Udp-Glcua And Udp-Glcnac |
| Alternative Antibody Names | Anti-Hyaluronan Synthase 3 antibodyAnti-Hyaluronate Synthase 3 antibodyAnti-Hyaluronic Acid Synthase 3 antibodyAnti-Ha Synthase 3 antibodyAnti-HAS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
