| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GDF3 (251-364) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GDF3 |
| Gene ID: |
9573 |
| Uniprot ID: |
GDF3_HUMAN |
| Immunogen Region: |
251-364 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 251-364 of human GDF3 (NP_065685.1). |
| Immunogen Sequence: |
AAIPVPKLSCKNLCHRHQLF INFRDLGWHKWIIAPKGFMA NYCHGECPFSLTISLNSSNY AFMQALMHAVDPEIPQAVCI PTKLSPISMLYQDNNDNVIL RHYEDMVVDECGCG |
| Post Translational Modifications | Synthesized as large precursor molecule that undergo proteolytic cleavage, releasing the pro-domain from the active, receptor binding, C-terminal region of the molecule. |
| Function | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO. Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto. |
| Protein Name | Growth/Differentiation Factor 3Gdf-3 |
| Cellular Localisation | SecretedCytoplasmMainly Accumulated In The Cytoplasm |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 3 antibodyAnti-Gdf-3 antibodyAnti-GDF3 antibodyAnti-UNQ222 antibodyAnti-PRO248 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
