| Tissue Specificity | Expressed in fetal and adult liver. |
| Function | Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (Probable). Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects. |
| Protein Name | Flavin-Containing Monooxygenase 5Fmo 5Baeyer-Villiger Monooxygenase 1Hbvmo1Dimethylaniline Monooxygenase N-Oxide-Forming 5Dimethylaniline Oxidase 5Nadph Oxidase |
| Cellular Localisation | Microsome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 5 antibodyAnti-Fmo 5 antibodyAnti-Baeyer-Villiger Monooxygenase 1 antibodyAnti-Hbvmo1 antibodyAnti-Dimethylaniline Monooxygenase N-Oxide-Forming 5 antibodyAnti-Dimethylaniline Oxidase 5 antibodyAnti-Nadph Oxidase antibodyAnti-FMO5 antibody |
Information sourced from Uniprot.org
