| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FMNL1 (900-1070) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FMNL1 |
| Gene ID: |
752 |
| Uniprot ID: |
FMNL1_HUMAN |
| Immunogen Region: |
900-1070 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2). |
| Immunogen Sequence: |
DLHFLDKAGSVSLDSVLADV RSLQRGLELTQREFVRQDDC MVLKEFLRANSPTMDKLLAD SKTAQEAFESVVEYFGENPK TTSPGLFFSLFSRFIKAYKK AEQEVEQWKKEAAAQEAGAD TPGKGEPPAPKSPPKARRPQ MDLISELKRRQQKEPLIYES DRDGAIEDIIT |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Myristoylation mediates membrane localization and blebbing. |
| Function | May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. |
| Protein Name | Formin-Like Protein 1Cll-Associated Antigen Kw-13Leukocyte Formin |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Cellular Localisation | CytoplasmCell MembraneLipid-AnchorCytoplasmic VesiclePhagosomeRecruited To Actin-Rich Phagosomes During PhagocytosisTranslocates To The Plasma Membrane Upon Activation By Rac1Isoform 3: CytoplasmCell CortexCell ProjectionBlebColocalized With F-Actin In Bleb Protrusions |
| Alternative Antibody Names | Anti-Formin-Like Protein 1 antibodyAnti-Cll-Associated Antigen Kw-13 antibodyAnti-Leukocyte Formin antibodyAnti-FMNL1 antibodyAnti-C17orf1 antibodyAnti-C17orf1B antibodyAnti-FMNL antibodyAnti-FRL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
