| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-EVL (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx. 50kDa band observed in lysates of cell line Jurkat (calculated MW of 44.8kDa according to NP_057421.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | EVL |
| Gene ID: | 51466 |
| Uniprot ID: | EVL_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_057421.1 |
| Immunogen Sequence: | SQPPNSSEAGRKP |
| Function | Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. |
| Protein Name | Ena/Vasp-Like ProteinEna/Vasodilator-Stimulated Phosphoprotein-Like |
| Database Links | Reactome: R-HSA-202433Reactome: R-HSA-376176Reactome: R-HSA-5663220 |
| Cellular Localisation | CytoplasmCytoskeletonStress FiberCell ProjectionLamellipodiumTargeted To The Leading Edge Of Lamellipodia And The Distal Tip Of Stress Fibers Through Interaction With A Number Of ProteinsIn Activated T-CellsLocalizes To The F-Actin Collar And The Distal Tip Of Microspikes |
| Alternative Antibody Names | Anti-Ena/Vasp-Like Protein antibodyAnti-Ena/Vasodilator-Stimulated Phosphoprotein-Like antibodyAnti-EVL antibodyAnti-RNB6 antibody |
Information sourced from Uniprot.org