| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ETS2 (165-345) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ETS2 |
| Gene ID: |
2114 |
| Uniprot ID: |
ETS2_HUMAN |
| Immunogen Region: |
165-345 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 165-345 of human ETS2 (NP_005230.1). |
| Immunogen Sequence: |
QMIKENQEKTEDQYEENSHL TSVPHWINSNTLGFGTEQAP YGMQTQNYPKGGLLDSMCPA STPSVLSSEQEFQMFPKSRL SSVSVTYCSVSQDFPGSNLN LLTNNSGTPKDHDSPENGAD SFESSDSLLQSWNSQSSLLD VQRVPSFESFEDDCSQSLCL NKPTMSFKDYIQERSDPVEQ G |
| Post Translational Modifications | Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation. |
| Function | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. |
| Protein Name | Protein C-Ets-2 |
| Database Links | Reactome: R-HSA-2559585 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein C-Ets-2 antibodyAnti-ETS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
