• Western blot analysis of extracts of Rat lung, using ETS2 antibody (STJ116696) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-ETS2 antibody (165-345) (STJ116696)

SKU:
STJ116696

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Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ETS2 (165-345) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ETS2
Gene ID: 2114
Uniprot ID: ETS2_HUMAN
Immunogen Region: 165-345
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 165-345 of human ETS2 (NP_005230.1).
Immunogen Sequence: QMIKENQEKTEDQYEENSHL TSVPHWINSNTLGFGTEQAP YGMQTQNYPKGGLLDSMCPA STPSVLSSEQEFQMFPKSRL SSVSVTYCSVSQDFPGSNLN LLTNNSGTPKDHDSPENGAD SFESSDSLLQSWNSQSSLLD VQRVPSFESFEDDCSQSLCL NKPTMSFKDYIQERSDPVEQ G
Post Translational Modifications Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation.
Function Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.
Protein Name Protein C-Ets-2
Database Links Reactome: R-HSA-2559585
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Protein C-Ets-2 antibody
Anti-ETS2 antibody

Information sourced from Uniprot.org

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