| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EAF2 |
| Gene ID: | 55840 |
| Uniprot ID: | EAF2_HUMAN |
| Immunogen Region: | 1-170 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human EAF2 (NP_060926.2). |
| Immunogen Sequence: | MNSAAGFSHLDRRERVLKLG ESFEKQPRCAFHTVRYDFKP ASIDTSSEGYLEVGEGEQVT ITLPNIEGSTPPVTVFKGSK KPYLKECILIINHDTGECRL EKLSSNITVKKTRVEGSSKI QYRKEQQQQQMWNSARTPNL VKHSPSEDKMSPASPIDDIE RELKAEASLM |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine, colon, adrenal, bone marrow, lymph node, spinal gland, stomach, thyroid, trachea, thymus, liver and leukocytes. |
| Function | Acts as a transcriptional transactivator of TCEA1 elongation activity. Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. |
| Protein Name | Ell-Associated Factor 2Testosterone-Regulated Apoptosis Inducer And Tumor Suppressor Protein |
| Database Links | Reactome: R-HSA-112382Reactome: R-HSA-674695Reactome: R-HSA-75955 |
| Cellular Localisation | Nucleus Speckle |
| Alternative Antibody Names | Anti-Ell-Associated Factor 2 antibodyAnti-Testosterone-Regulated Apoptosis Inducer And Tumor Suppressor Protein antibodyAnti-EAF2 antibodyAnti-TRAITS antibodyAnti-BM-040 antibody |
Information sourced from Uniprot.org