| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-EAF2 (1-170) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:100 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EAF2 |
| Gene ID: |
55840 |
| Uniprot ID: |
EAF2_HUMAN |
| Immunogen Region: |
1-170 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human EAF2 (NP_060926.2). |
| Immunogen Sequence: |
MNSAAGFSHLDRRERVLKLG ESFEKQPRCAFHTVRYDFKP ASIDTSSEGYLEVGEGEQVT ITLPNIEGSTPPVTVFKGSK KPYLKECILIINHDTGECRL EKLSSNITVKKTRVEGSSKI QYRKEQQQQQMWNSARTPNL VKHSPSEDKMSPASPIDDIE RELKAEASLM |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine, colon, adrenal, bone marrow, lymph node, spinal gland, stomach, thyroid, trachea, thymus, liver and leukocytes. |
| Function | Acts as a transcriptional transactivator of TCEA1 elongation activity. Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo. |
| Protein Name | Ell-Associated Factor 2Testosterone-Regulated Apoptosis Inducer And Tumor Suppressor Protein |
| Database Links | Reactome: R-HSA-112382Reactome: R-HSA-674695Reactome: R-HSA-75955 |
| Cellular Localisation | Nucleus Speckle |
| Alternative Antibody Names | Anti-Ell-Associated Factor 2 antibodyAnti-Testosterone-Regulated Apoptosis Inducer And Tumor Suppressor Protein antibodyAnti-EAF2 antibodyAnti-TRAITS antibodyAnti-BM-040 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
