| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHORDC1 (60-160) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHORDC1 |
| Gene ID: |
26973 |
| Uniprot ID: |
CHRD1_HUMAN |
| Immunogen Region: |
60-160 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2). |
| Immunogen Sequence: |
TKGRHNSEKPPEPVKPEVKT TEKKELCELKPKFQEHIIQA PKPVEAIKRPSPDEPMTNLE LKISASLKQALDKLKLSSGN EENKKEEDNDEIKIGTSCKN G |
| Tissue Specificity | Underexpressed in many breast and lung cancers. |
| Function | Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis. |
| Protein Name | Cysteine And Histidine-Rich Domain-Containing Protein 1Chord Domain-Containing Protein 1Chord-Containing Protein 1Chp-1Protein Morgana |
| Alternative Antibody Names | Anti-Cysteine And Histidine-Rich Domain-Containing Protein 1 antibodyAnti-Chord Domain-Containing Protein 1 antibodyAnti-Chord-Containing Protein 1 antibodyAnti-Chp-1 antibodyAnti-Protein Morgana antibodyAnti-CHORDC1 antibodyAnti-CHP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
