• Western blot analysis of extracts of various cell lines, using CDK20 antibody (STJ113204) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-CDK20 antibody (1-275) (STJ113204)

SKU:
STJ113204

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDK20 (1-275) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDK20
Gene ID: 23552
Uniprot ID: CDK20_HUMAN
Immunogen Region: 1-275
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human CDK20 (NP_001164110.1).
Immunogen Sequence: MDQYCILGRIGEGAHGIVFK AKHVETGEIVALKKVALRRL EDGFPNQALREIKALQEMED NQYVVQLKAVFPHGGGFVLA FEFMLSDLAEVVRHAQRPLA QAQVKSYLQMLLKGVAFCHA NNIVHRDLKPANLLISASGQ LKIADFGLARVFSPDGSRLY THQVATRSVGCIMGELLNGS PLFPGKNDIEQLCYVLRILG TPNPQVWPELTELPDYNKIS FKEQVPMPLEEVLPDVSPQ
Function Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling. Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Protein Name Cyclin-Dependent Kinase 20
Cdk-Activating Kinase P42
Cak-Kinase P42
Cell Cycle-Related Kinase
Cell Division Protein Kinase 20
Cyclin-Dependent Protein Kinase H
Cyclin-Kinase-Activating Kinase P42
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Cilium
Alternative Antibody Names Anti-Cyclin-Dependent Kinase 20 antibody
Anti-Cdk-Activating Kinase P42 antibody
Anti-Cak-Kinase P42 antibody
Anti-Cell Cycle-Related Kinase antibody
Anti-Cell Division Protein Kinase 20 antibody
Anti-Cyclin-Dependent Protein Kinase H antibody
Anti-Cyclin-Kinase-Activating Kinase P42 antibody
Anti-CDK20 antibody
Anti-CCRK antibody
Anti-CDCH antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance