Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CDK20 (1-275) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CDK20 |
Gene ID: |
23552 |
Uniprot ID: |
CDK20_HUMAN |
Immunogen Region: |
1-275 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human CDK20 (NP_001164110.1). |
Immunogen Sequence: |
MDQYCILGRIGEGAHGIVFK AKHVETGEIVALKKVALRRL EDGFPNQALREIKALQEMED NQYVVQLKAVFPHGGGFVLA FEFMLSDLAEVVRHAQRPLA QAQVKSYLQMLLKGVAFCHA NNIVHRDLKPANLLISASGQ LKIADFGLARVFSPDGSRLY THQVATRSVGCIMGELLNGS PLFPGKNDIEQLCYVLRILG TPNPQVWPELTELPDYNKIS FKEQVPMPLEEVLPDVSPQ |
Function | Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling. Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'. |
Protein Name | Cyclin-Dependent Kinase 20Cdk-Activating Kinase P42Cak-Kinase P42Cell Cycle-Related KinaseCell Division Protein Kinase 20Cyclin-Dependent Protein Kinase HCyclin-Kinase-Activating Kinase P42 |
Cellular Localisation | NucleusCytoplasmCell ProjectionCilium |
Alternative Antibody Names | Anti-Cyclin-Dependent Kinase 20 antibodyAnti-Cdk-Activating Kinase P42 antibodyAnti-Cak-Kinase P42 antibodyAnti-Cell Cycle-Related Kinase antibodyAnti-Cell Division Protein Kinase 20 antibodyAnti-Cyclin-Dependent Protein Kinase H antibodyAnti-Cyclin-Kinase-Activating Kinase P42 antibodyAnti-CDK20 antibodyAnti-CCRK antibodyAnti-CDCH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance