Host: |
Rabbit |
Applications: |
WB/FC |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-CD80 (38-245) is suitable for use in Western Blot and Flow Cytometry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S5206RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000FC 1:100-1:500 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
Cd80 |
Gene ID: |
12519 |
Uniprot ID: |
CD80_MOUSE |
Immunogen Region: |
38-245 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 38-245 of mouse CD80 (NP_033985.3) |
Immunogen Sequence: |
VDEQLSKSVKDKVLLPCRYN SPHEDESEDRIYWQKHDKVV LSVIAGKLKVWPEYKNRTLY DNTTYSLIILGLVLSDRGTY SCVVQKKERGTYEVKHLALV KLSIKADFSTPNITESGNPS ADTKRITCFASGGFPKPRFS WLENGRELPGINTTISQDPE SELYTISSQLDFNTTRNHTI KCLIKYGDAHVSEDFTWEKP PEDPPDSK |
Tissue Specificity | Expressed on activated B-cells, gamma interferon stimulated monocytes and non-circulating B-cell malignancies. |
Function | Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. |
Protein Name | T-Lymphocyte Activation Antigen Cd80Activation B7-1 AntigenB7Cd Antigen Cd80 |
Database Links | Reactome: R-MMU-1257604Reactome: -MMU-389356Reactome: -MMU-389357Reactome: -MMU-389359Reactome: -MMU-389513Reactome: -MMU-6811558 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-T-Lymphocyte Activation Antigen Cd80 antibodyAnti-Activation B7-1 Antigen antibodyAnti-B7 antibodyAnti-Cd Antigen Cd80 antibodyAnti-Cd80 antibodyAnti-B7 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance