| Function | Microtubule-binding centrosomal protein required for centriole cohesion, independently of the centrosome-associated protein/CEP250 and rootletin/CROCC linker. In interphase, required for anchoring microtubule at the mother centriole subdistal appendages and for centrosome positioning. During mitosis, may be involved in spindle assembly and chromatin alignment by regulating the organization of spindle microtubules into a symmetrical structure. Has been proposed to play a role in CEP170 recruitment to centrosomes. However, this function could not be confirmed. Plays a non-essential role in ciliogenesis. |
| Protein Name | Centrosomal Protein Ccdc61Coiled-Coil Domain-Containing Protein 61Vfl3 Homolog |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentriolar SatelliteCilium Basal BodyLocalization At The Centriolar Satellite Is Dependent On Intact Microtubule NetworkLocalizes At The Centriole Subdistal Appendages And Proximal EndsLocalized To Centrosomal/Satellite-Like Structures With The Onset Of Centrosome Separation In Early G2 |
| Alternative Antibody Names | Anti-Centrosomal Protein Ccdc61 antibodyAnti-Coiled-Coil Domain-Containing Protein 61 antibodyAnti-Vfl3 Homolog antibodyAnti-CCDC61 antibody |
Information sourced from Uniprot.org
