Anti-ANTXR1/TEM8 antibody [SAA1962] (STJA0020390)

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STJA0020390
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Anthrax Toxin Receptor 1 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1962
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: ANTXR1
Gene ID: 84168
Uniprot ID: ANTR1_HUMAN
Function Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. (Microbial infection) Acts as a receptor for protective antigen (PA) of B.anthracis.
Protein Name Anthrax Toxin Receptor 1
Tumor Endothelial Marker 8
Database Links Reactome: R-HSA-5210891
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Lamellipodium Membrane
Filopodium Membrane
At The Membrane Of Lamellipodia And At The Tip Of Actin-Enriched Filopodia
Colocalizes With Actin At The Base Of Lamellipodia
Alternative Antibody Names Anti-Anthrax Toxin Receptor 1 antibody
Anti-Tumor Endothelial Marker 8 antibody
Anti-ANTXR1 antibody
Anti-ATR antibody
Anti-TEM8 antibody

Information sourced from Uniprot.org

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