| Tissue Specificity | Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues. |
| Post Translational Modifications | The prodomain and the metalloprotease domain are cleaved during the epididymal maturation of the spermatozoa. |
| Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 2Adam 2Cancer/Testis Antigen 15Ct15Fertilin Subunit BetaPh-30Ph30Ph30-Beta |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 2 antibodyAnti-Adam 2 antibodyAnti-Cancer/Testis Antigen 15 antibodyAnti-Ct15 antibodyAnti-Fertilin Subunit Beta antibodyAnti-Ph-30 antibodyAnti-Ph30 antibodyAnti-Ph30-Beta antibodyAnti-ADAM2 antibodyAnti-FTNB antibody |
Information sourced from Uniprot.org
