ZMPSTE24 Positive Control for STJ503602 peptide (STJ505266)

SKU:
STJ505266-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: ZMPSTE24 Positive Control for STJ503602 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ZMPSTE24
Gene ID: 10269
Uniprot ID: FACE1_HUMAN
Specificity: This is positive control is recommended for use in combination with ZMPSTE24 antibody STJ503602.
Tissue Specificity Widely expressed. High levels in kidney, prostate, testis and ovary.
Function Transmembrane metalloprotease whose catalytic activity is critical for processing lamin A/LMNA on the inner nuclear membrane and clearing clogged translocons on the endoplasmic reticulum. Proteolytically removes the C-terminal three residues of farnesylated proteins. Plays also an antiviral role independently of its protease activity by restricting enveloped RNA and DNA viruses, including influenza A, Zika, Ebola, Sindbis, vesicular stomatitis, cowpox, and vaccinia. Mechanistically, controls IFITM antiviral pathway to hinder viruses from breaching the endosomal barrier by modulating membrane fluidity.
Peptide Name Caax Prenyl Protease 1 Homolog
Farnesylated Proteins-Converting Enzyme 1
Face-1
Prenyl Protein-Specific Endoprotease 1
Zinc Metalloproteinase Ste24 Homolog
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Nucleus Inner Membrane
Early Endosome Membrane
Late Endosome Membrane
Alternative Peptide Names Caax Prenyl Protease 1 Homolog protein
Farnesylated Proteins-Converting Enzyme 1 protein
Face-1 protein
Prenyl Protein-Specific Endoprotease 1 protein
Zinc Metalloproteinase Ste24 Homolog protein
ZMPSTE24 protein
FACE1 protein
STE24 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance