| Applications: |
ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.058ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This ADAMTS7 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
3 hrs |
| Gene Symbol: |
Adamts7 |
| Gene ID: |
315879 |
| Uniprot ID: |
ATS7_RAT |
| Immunogen Region: |
Ready-To-Use |
| Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Detected in liver, ovary, kidney, testicle, lung and embryo. |
| Post Translational Modifications | Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs. N- and C-glycosylations can also facilitate secretion. O-glycosylated proteoglycan. Contains chondroitin sulfate. May be cleaved by a furin endopeptidase. The precursor is sequentially processed. |
| Function | Metalloprotease that may play a role in the degradation of COMP. |
| Protein Name | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7Adam-Ts 7Adam-Ts7Adamts-7Compase |
| Database Links | Reactome: R-RNO-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixAlso Found Associated With The External Cell Surface |
| Alternative ELISA Names | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 ELISA kitAdam-Ts 7 ELISA kitAdam-Ts7 ELISA kitAdamts-7 ELISA kitCompase ELISA kitAdamts7 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
