| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse Serum albumin/ALB-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: |
Mouse Serum Albumin, His Tag immobilized on CM5 Chip can bind Mouse FcRn, His Tag with an affinity constant of 54.53 nM as determined in SPR assay (Biacore T200). |
| Gene Symbol: |
Alb |
| Gene ID: |
11657 |
| Uniprot ID: |
ALBU_MOUSE |
| Immunogen Region: |
Glu25-Ala608 |
| Immunogen: |
Recombinant Mouse Serum albumin/ALB Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu25-Ala608) of mouse Serum albumin/ALB (Accession #NP_033784.2) fused with a 6×His tag at the C-terminus. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin. |
| Protein Name | Albumin |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-159418Reactome: -MMU-189451Reactome: -MMU-189483Reactome: -MMU-2168880Reactome: -MMU-381426Reactome: -MMU-8957275Reactome: -MMU-8964058Reactome: -MMU-9707564Reactome: -MMU-9749641Reactome: -MMU-9757110Reactome: -MMU-9793528 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Albumin proteinAlb proteinAlb-1 proteinAlb1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
