Mouse PLAT/tPA protein (Recombinant) (N-His) (STJP011065)

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STJP011065
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse PLAT/tPA-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Plat
Gene ID: 18791
Uniprot ID: TPA_MOUSE
Immunogen Region: Asp316-Gln559
Immunogen: Mus musculus (Mouse)
Function Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy.
Protein Name Tissue-Type Plasminogen Activator
T-Pa
T-Plasminogen Activator
Tpa Cleaved Into - Tissue-Type Plasminogen Activator Chain A - Tissue-Type Plasminogen Activator Chain B
Database Links Reactome: R-MMU-186797
Reactome: -MMU-75205
Cellular Localisation Secreted
Extracellular Space
Alternative Protein Names Tissue-Type Plasminogen Activator protein
T-Pa protein
T-Plasminogen Activator protein
Tpa Cleaved Into - Tissue-Type Plasminogen Activator Chain A - Tissue-Type Plasminogen Activator Chain B protein
Plat protein

Information sourced from Uniprot.org

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