| Applications: |
ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
12.5pg/mL |
| Detection Limit: |
31.2-2000pg/mL |
| Short Description: |
This NEFL Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
Nefl |
| Gene ID: |
18039 |
| Uniprot ID: |
NFL_MOUSE |
| Sample Type: |
serum, plasma, cerebrospinal fluid or other biological fluids. |
| Tissue Specificity | Expressed in the sciatic nerve (at protein level). |
| Post Translational Modifications | O-glycosylated. Phosphorylated in the head and rod regions by the PKC kinase PKN1, leading to the inhibition of polymerization. Ubiquitinated in the presence of TRIM2 and UBE2D1. |
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Light PolypeptideNf-L68 Kda Neurofilament ProteinNeurofilament Triplet L Protein |
| Database Links | Reactome: R-MMU-438066Reactome: -MMU-5673001 |
| Cellular Localisation | Cell ProjectionAxonCytoplasmCytoskeleton |
| Alternative ELISA Names | Neurofilament Light Polypeptide ELISA kitNf-L ELISA kit68 Kda Neurofilament Protein ELISA kitNeurofilament Triplet L Protein ELISA kitNefl ELISA kitNf68 ELISA kitNfl ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
