• Mouse IL-21R/CD360 protein (Recombinant) (C-hFc) (STJP002458)
  • Mouse IL-21R/CD360 protein (Recombinant) (C-hFc) (STJP002458)

Mouse IL-21R/CD360 protein (Recombinant) (C-hFc) (STJP002458)

SKU:
STJP002458-100

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Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse IL-21R/CD360-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 50mM Tris, 100mM NaCl, pH 7.4, 20% gly, 0.3mM DTT.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its ability to inhibit Mouse IL-21-induced Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 0.2-1.5 Mu g/mL in the presence of 50 ng/mL of recombinant mouse IL-21.
Gene Symbol: Il21r
Gene ID: 60504
Uniprot ID: IL21R_MOUSE
Immunogen Region: Cys20-Pro236
Immunogen: Recombinant Mouse IL-21R/CD360 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Cys20-Pro236) of mouse IL-21R/CD360 (Accession #AAL82636.1) fused with a hFc tag at the C-terminus.
Post Translational Modifications C-mannosylated at Trp-214 in the WSXWS motif, the sugar chain makes extensive hydrogen bonds with Asn-73 sugar, and bridges the two fibronectin domains transforming the V-shaped receptor into an A-frame.
Function This is a receptor for interleukin-21.
Protein Name Interleukin-21 Receptor
Il-21 Receptor
Il-21r
Lymphocyte Receptor Beta
Lr-Beta
Novel Cytokine Receptor 8
Nr8
Novel Interleukin Receptor
Cd Antigen Cd360
Database Links Reactome: R-MMU-9020958
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-21 Receptor protein
Il-21 Receptor protein
Il-21r protein
Lymphocyte Receptor Beta protein
Lr-Beta protein
Novel Cytokine Receptor 8 protein
Nr8 protein
Novel Interleukin Receptor protein
Cd Antigen Cd360 protein
Il21r protein
Nilr protein

Information sourced from Uniprot.org

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