Name: Mouse Galectin-1/LGALS1 protein (Recombinant) (C-hFC) (STJP003047)
SKU: STJP003047
Availability: InStock

Mouse Galectin-1/LGALS1 protein (Recombinant) (C-hFC) (STJP003047)

SKU:

STJP003047

$120.83 - $370.58

Host:	HEK293 cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation:	Lyophilised from a 0.22 Mu m filtered solution of PBS, 1mM DTT, 1mM EDTA, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method:	< 1 EU/Mu g of the protein by LAL method.
Immunoreactivity:	Measured by its ability to agglutinate mouse red blood cells. The ED₅₀ for this effect is 6.25-12.5 Mu g/mL.

Gene Symbol:	Lgals1
Gene ID:	16852
Uniprot ID:	LEG1_MOUSE
Immunogen Region:	Ala2-Glu135
Immunogen:	Recombinant Mouse Galectin-1/LGALS1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala2-Glu135 ) of Mouse Galectin-1/LGALS1 (Accession #NP_032521.1) fused with no tag.
Immunogen Sequence:	PNRRTCVFFEAPGVRGSTKT LGELLDTGTELPRAIRCLYS RCCFGIWNLTQDRAQVEMQG CRDSDEPGCESLHCDPSPRA HPSPGSTLFTCSCGTDFCNA NYSHLPPPGSPGTPGSQGPQ AAPGES

Function	Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69.
Protein Name	Galectin-1 Gal-1 14 Kda Lectin Beta-Galactoside-Binding Lectin L-14-I Galaptin Lactose-Binding Lectin 1 Lectin Galactoside-Binding Soluble 1 S-Lac Lectin 1
Database Links	Reactome: R-MMU-381426 Reactome: -MMU-8957275
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Cytoplasm Can Be Secreted The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names	Galectin-1 protein Gal-1 protein 14 Kda Lectin protein Beta-Galactoside-Binding Lectin L-14-I protein Galaptin protein Lactose-Binding Lectin 1 protein Lectin Galactoside-Binding Soluble 1 protein S-Lac Lectin 1 protein Lgals1 protein Gbp protein

Information sourced from Uniprot.org

Model	Name	Host
STJP000780	Human Galectin-1/LGALS1 protein (Recombinant) (No tag) (STJP000780)	E. coli
STJP002828	Mouse BTLA protein (Recombinant) (C-hFC) (STJP002828)	HEK293 cells
STJP002876	Mouse CD276 protein (Recombinant) (C-hFc) (STJP002876)	HEK293 cells
STJP001430	Mouse CD24 protein (Recombinant) (C-hFc) (STJP001430)	HEK293 cells
STJP001508	Mouse CD8a protein (Recombinant) (C-hFc) (STJP001508)	HEK293 cells

Mouse Galectin-1/LGALS1 protein (Recombinant) (C-hFC) (STJP003047)