| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse CLEC9A/CD370-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
| Formulation: |
Supplied as a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Clec9a |
| Gene ID: |
232414 |
| Uniprot ID: |
CLC9A_MOUSE |
| Immunogen Region: |
Lys57-Ile264 |
| Immunogen: |
Recombinant Mouse CLEC9A/CD370 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys57-Ile264) of mouse CLEC9A/CD370 (Accession #NP_001192292.1) fused with a hFc tag at the C-terminus. |
| Post Translational Modifications | Isoform 1: Not glycosylated. Isoform 4: N-glycosylated. |
| Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
| Protein Name | C-Type Lectin Domain Family 9 Member ADendritic Cell Natural Killer Lectin Group Receptor 1Cd Antigen Cd370 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | C-Type Lectin Domain Family 9 Member A proteinDendritic Cell Natural Killer Lectin Group Receptor 1 proteinCd Antigen Cd370 proteinClec9a proteinDngr-1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
