| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse CD10/MME-N-His protein was developed from hek293 cells and has a target region of N-His. For use in research applications. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Endotoxin: |
Less than 1EU per Mu g by the LAL method. |
| Gene Symbol: |
Mme |
| Gene ID: |
17380 |
| Uniprot ID: |
NEP_MOUSE |
| Immunogen Region: |
Tyr52-Trp750 |
| Immunogen: |
Recombinant Mouse CD10/MME Protein is expressed from Expi293 with His tag at the N-terminal.；It contains Tyr52-Trp750. |
| Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of the atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| Protein Name | NeprilysinAtriopeptidaseEnkephalinaseNeutral Endopeptidase 24.11NepNeutral EndopeptidaseSkin Fibroblast ElastaseSfeCd Antigen Cd10 |
| Database Links | Reactome: R-MMU-2022377Reactome: -MMU-5578768Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Neprilysin proteinAtriopeptidase proteinEnkephalinase proteinNeutral Endopeptidase 24.11 proteinNep proteinNeutral Endopeptidase proteinSkin Fibroblast Elastase proteinSfe proteinCd Antigen Cd10 proteinMme protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
