Mouse BAFF/CD257 (Tumor Necrosis Factor Ligand Superfamily Member 13b) Antibody Pair (STJAP00564)

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STJAP00564-50
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Host: Goat/Goat
Applications: ELISA
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : This BAFF/CD257 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
Conjugation: Unconjugated/Biotin
Formulation: Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.
Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5.
Purification: Capture Purification: Antigen Affinity.
Detection Purification: Antigen Affinity.
Concentration: 0.5 mg/mL
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Determination Method: Colormetric
Gene Symbol: Tnfsf13b
Gene ID: 24099
Uniprot ID: TN13B_MOUSE
Immunogen: Capture immunogen: Recombinant Mouse BAFF/CD257 protien.
Detection Immunogen: Recombinant Mouse BAFF/CD257 protien.
Sample Type: Serum, plasma and other biological fluids
Post Translational Modifications The soluble form derives from the membrane form by proteolytic processing. Isoform 2 is not efficiently shed from the membrane unlike isoform 1.
Function Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Isoform 2 seems to inhibit isoform 1 secretion and bioactivity.
Protein Name Tumor Necrosis Factor Ligand Superfamily Member 13b
B-Cell-Activating Factor
Baff
Cd Antigen Cd257 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 13b - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 13b - Soluble Form
Database Links Reactome: R-MMU-5668541
Reactome: -MMU-5669034
Reactome: -MMU-5676594
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Tumor Necrosis Factor Ligand Superfamily Member 13b
Soluble Form: Secreted
Alternative Antibody Pair Names Tumor Necrosis Factor Ligand Superfamily Member 13b antibody pair
B-Cell-Activating Factor antibody pair
Baff antibody pair
Cd Antigen Cd257 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 13b - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 13b - Soluble Form antibody pair
Tnfsf13b antibody pair
Baff antibody pair

Information sourced from Uniprot.org

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