• Human UBE2I (Ubiquitin Conjugating Enzyme E2I) Sandwich ELISA Kit (STJE0012895)

Human UBE2I (Ubiquitin Conjugating Enzyme E2I) Sandwich ELISA Kit (STJE0012895)

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STJE0012895

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.053ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This UBE2I Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: UBE2I
Gene ID: 7329
Uniprot ID: UBC9_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
Post Translational Modifications Phosphorylation at Ser-71 significantly enhances SUMOylation activity.
Function Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.
Protein Name Sumo-Conjugating Enzyme Ubc9
Ring-Type E3 Sumo Transferase Ubc9
Sumo-Protein Ligase
Ubiquitin Carrier Protein 9
Ubiquitin Carrier Protein I
Ubiquitin-Conjugating Enzyme E2 I
Ubiquitin-Protein Ligase I
P18
Database Links Reactome: R-HSA-1221632
Reactome: R-HSA-196791
Reactome: R-HSA-3065678
Reactome: R-HSA-3108214
Reactome: R-HSA-3232118
Reactome: R-HSA-3232142
Reactome: R-HSA-3899300
Reactome: R-HSA-4085377
Reactome: R-HSA-4090294
Reactome: R-HSA-4551638
Reactome: R-HSA-4570464
Reactome: R-HSA-4615885
Reactome: R-HSA-4655427
Reactome: R-HSA-4755510
Reactome: R-HSA-5693565
Reactome: R-HSA-5693607
Reactome: R-HSA-5696395
Reactome: R-HSA-8866904
Reactome: R-HSA-9615933
Reactome: R-HSA-9683610
Reactome: R-HSA-9694631
Reactome: R-HSA-9735871
Reactome: R-HSA-9793242
Cellular Localisation Nucleus
Cytoplasm
Perinuclear Region
Mainly Nuclear
In Spermatocytes
Localizes In Synaptonemal Complexes
Recruited By Bcl11a Into The Nuclear Body
Alternative ELISA Names Sumo-Conjugating Enzyme Ubc9 ELISA kit
Ring-Type E3 Sumo Transferase Ubc9 ELISA kit
Sumo-Protein Ligase ELISA kit
Ubiquitin Carrier Protein 9 ELISA kit
Ubiquitin Carrier Protein I ELISA kit
Ubiquitin-Conjugating Enzyme E2 I ELISA kit
Ubiquitin-Protein Ligase I ELISA kit
P18 ELISA kit
UBE2I ELISA kit
UBC9 ELISA kit
UBCE9 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance