Human TNFRSF25/DR3 protein (Recombinant) (C-hFc) (STJP002627)

SKU:
STJP002627

€121.88 - €289.38
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human TNFRSF25/DR3-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF25
Gene ID: 8718
Uniprot ID: TNR25_HUMAN
Immunogen Region: Met1-Gln199
Immunogen: Recombinant Human TNFRSF25/DR3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Gln199) of human TNFRSF25/DR3 (Accession #Q93038) fused with a hFc tag at the C-terminus.
Post Translational Modifications (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated.
Function Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 25
Apo-3
Apoptosis-Inducing Receptor Air
Apoptosis-Mediating Receptor Dr3
Apoptosis-Mediating Receptor Tramp
Death Receptor 3
Lymphocyte-Associated Receptor Of Death
Lard
Protein Wsl
Protein Wsl-1
Database Links Reactome: R-HSA-5669034
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cell Membrane
Isoform 9: Cell Membrane
Isoform 11: Cell Membrane
Isoform 3: Secreted
Isoform 4: Secreted
Isoform 5: Secreted
Isoform 6: Secreted
Isoform 7: Secreted
Isoform 8: Secreted
Isoform 10: Secreted
Isoform 12: Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 25 protein
Apo-3 protein
Apoptosis-Inducing Receptor Air protein
Apoptosis-Mediating Receptor Dr3 protein
Apoptosis-Mediating Receptor Tramp protein
Death Receptor 3 protein
Lymphocyte-Associated Receptor Of Death protein
Lard protein
Protein Wsl protein
Protein Wsl-1 protein
TNFRSF25 protein
APO3 protein
DDR3 protein
DR3 protein
TNFRSF12 protein
WSL protein
WSL1 protein
UNQ455 protein
PRO779 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance