Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human TNFRSF25/DR3-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TNFRSF25 |
Gene ID: |
8718 |
Uniprot ID: |
TNR25_HUMAN |
Immunogen Region: |
Met1-Gln199 |
Immunogen: |
Recombinant Human TNFRSF25/DR3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Gln199) of human TNFRSF25/DR3 (Accession #Q93038) fused with a hFc tag at the C-terminus. |
Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25Apo-3Apoptosis-Inducing Receptor AirApoptosis-Mediating Receptor Dr3Apoptosis-Mediating Receptor TrampDeath Receptor 3Lymphocyte-Associated Receptor Of DeathLardProtein WslProtein Wsl-1 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 9: Cell MembraneIsoform 11: Cell MembraneIsoform 3: SecretedIsoform 4: SecretedIsoform 5: SecretedIsoform 6: SecretedIsoform 7: SecretedIsoform 8: SecretedIsoform 10: SecretedIsoform 12: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 25 proteinApo-3 proteinApoptosis-Inducing Receptor Air proteinApoptosis-Mediating Receptor Dr3 proteinApoptosis-Mediating Receptor Tramp proteinDeath Receptor 3 proteinLymphocyte-Associated Receptor Of Death proteinLard proteinProtein Wsl proteinProtein Wsl-1 proteinTNFRSF25 proteinAPO3 proteinDDR3 proteinDR3 proteinTNFRSF12 proteinWSL proteinWSL1 proteinUNQ455 proteinPRO779 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance