| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human SIRP-gamma/SIRPB2/CD172g-C-Fc protein was developed from hek293 cells and has a target region of C-Fc. For use in research applications. |
| Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SIRPG |
| Gene ID: |
55423 |
| Uniprot ID: |
SIRPG_HUMAN |
| Immunogen Region: |
Glu29-Pro360 |
| Immunogen: |
Recombinant Human SIRP-gamma/SIRPB2/CD172g Protein is produced by Human cells expression system. The target protein is expressed with sequence (Glu29-Pro360) of human SIRPG/SIRPB2 (Accession #Q9P1W8) fused with an Fc tag at the C-terminus. |
| Function | Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. |
| Protein Name | Signal-Regulatory Protein GammaSirp-GammaCd172 Antigen-Like Family Member BSignal-Regulatory Protein Beta-2Sirp-B2Sirp-Beta-2Cd Antigen Cd172g |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-391160 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Signal-Regulatory Protein Gamma proteinSirp-Gamma proteinCd172 Antigen-Like Family Member B proteinSignal-Regulatory Protein Beta-2 proteinSirp-B2 proteinSirp-Beta-2 proteinCd Antigen Cd172g proteinSIRPG proteinSIRPB2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
