Applications: |
CLIA |
Reactivity: |
Human |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Sensitivity: |
37.5pg/mL |
Detection Limit: |
62.5~4000pg/mL |
Short Description: |
This human MSR1 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes. |
Storage Instruction: |
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual. |
Assay Time: |
3.5h |
Detection: |
Chemiluminescence |
Gene Symbol: |
MSR1 |
Gene ID: |
4481 |
Uniprot ID: |
MSRE_HUMAN |
Specificity: |
This kit recognizes Human MSR1 in samples. No significant cross-reactivity or interference between Human MSR1 and analogues was observed. |
Sample Type: |
Serum, plasma and other biological fluids |
Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. |
Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
Database Links | Reactome: R-HSA-3000480 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative CLIA Names | Macrophage Scavenger Receptor Types I And Ii CLIA kitMacrophage Acetylated Ldl Receptor I And Ii CLIA kitScavenger Receptor Class A Member 1 CLIA kitCd Antigen Cd204 CLIA kitMSR1 CLIA kitSCARA1 CLIA kit |
Specificity | This kit recognizes Human MSR1 in samples. No significant cross-reactivity or interference between Human MSR1 and analogues was observed. |
Reproducibility | Both intra-CV and inter-CV are |
Information sourced from Uniprot.org
Item | Specifications | Storage |
Micro CLIA Plate (Dismountable) | 96T: 8 wells ×12 strips strips | -20℃, 6 months |
Reference Standard | 96T: 2 vials 48T: 1 vial | -20℃, 6 months |
Concentrated Biotinylated Detection Ab (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃, 6 months |
Concentrated HRP Conjugate (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃ (Protect from light), 6 months |
Reference Standard & Sample Diluent | 1 vial, 20 mL | 2-8°C, 6 months |
Biotinylated Detection Ab Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
HRP Conjugate Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
Concentrated Wash Buffer (25×) | 1 vial, 30 mL | 2-8°C, 6 months |
Substrate Reagent A | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Substrate Reagent B | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Plate Sealer | 5 pieces | |
Manual | 1 copy | |
Certificate of Analysis | 1 copy | |
Sample Type | Range (%) | Average Recovery (%) |
Serum(n=8) | 87-101 | 92 |
EDTA plasma(n=8) | 87-100 | 92 |
Cell culture media(n=8) | 94-108 | 99 |
| Intra-assay Precision | Intra-assay Precision | Intra-assay Precision | Inter-assay Precision | Inter-assay Precision | Inter-assay Precision |
Sample | 1.00 | 2.00 | 3.00 | 1.00 | 2.00 | 3.00 |
n | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 |
Mean (pg/mL) | 205.70 | 398.07 | 1893.94 | 188.32 | 425.69 | 1716.38 |
Standard deviation | 20.26 | 35.83 | 199.24 | 21.24 | 44.14 | 159.28 |
CV (%) | 9.85 | 9.00 | 10.52 | 11.28 | 10.37 | 9.28 |
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance