Human MOCS2 protein (Recombinant) (N-GST & C-His) (STJP010811)

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STJP010811
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MOCS2-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MOCS2
Gene ID: 4338
Uniprot ID: MOC2A_HUMAN
Immunogen Region: Val2-Gly88
Immunogen: Homo sapiens (Human)
Post Translational Modifications C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
Function Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
Protein Name Molybdopterin Synthase Sulfur Carrier Subunit
Moco1-A
Molybdenum Cofactor Synthesis Protein 2 Small Subunit
Molybdenum Cofactor Synthesis Protein 2a
Mocs2a
Molybdopterin-Synthase Small Subunit
Sulfur Carrier Protein Mocs2a
Database Links Reactome: R-HSA-947581
Cellular Localisation Cytoplasm
Cytosol
Alternative Protein Names Molybdopterin Synthase Sulfur Carrier Subunit protein
Moco1-A protein
Molybdenum Cofactor Synthesis Protein 2 Small Subunit protein
Molybdenum Cofactor Synthesis Protein 2a protein
Mocs2a protein
Molybdopterin-Synthase Small Subunit protein
Sulfur Carrier Protein Mocs2a protein
MOCS2 protein
MOCO1 protein

Information sourced from Uniprot.org

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