| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human Lipopolysaccharide-binding/LBP-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.2 Mu m filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LBP |
| Gene ID: |
3929 |
| Uniprot ID: |
LBP_HUMAN |
| Immunogen Region: |
Ala26-Val481 |
| Immunogen: |
Recombinant Human Lipopolysaccharide-binding protein/LBP Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Ala26-Val481) of human LBP/Lipopolysaccharide-binding protein (Accession #P18428) fused with |
| Function | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide. |
| Protein Name | Lipopolysaccharide-Binding ProteinLbp |
| Database Links | Reactome: R-HSA-166016Reactome: R-HSA-166020Reactome: R-HSA-5686938Reactome: R-HSA-6785807 |
| Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
| Alternative Protein Names | Lipopolysaccharide-Binding Protein proteinLbp proteinLBP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
