Human KIN protein (Recombinant) (N-His) (STJP010715)

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STJP010715
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human KIN-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: KIN
Gene ID: 22944
Uniprot ID: KIN17_HUMAN
Immunogen Region: Met1-Ile142
Immunogen: Homo sapiens (Human)
Function Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo. Binds via its C-terminal domain to RNA in vitro.
Protein Name Dna/Rna-Binding Protein Kin17
Binding To Curved Dna
Kin - Antigenic Determinant Of Reca Protein Homolog
Database Links Reactome: R-HSA-8876725
Cellular Localisation Nucleus
Cytoplasm
During S Phase
Strongly Associated With The Nuclear Matrix
And To Chromosomal Dna In The Presence Of Dna Damage
Also Shows Cytoplasmic Localization In Elongated Spermatids
Alternative Protein Names Dna/Rna-Binding Protein Kin17 protein
Binding To Curved Dna protein
Kin - Antigenic Determinant Of Reca Protein Homolog protein
KIN protein
BTCD protein
KIN17 protein

Information sourced from Uniprot.org

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