| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human KIF18A-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | KIF18A |
| Gene ID: | 81930 |
| Uniprot ID: | KI18A_HUMAN |
| Immunogen Region: | Met1-Lys453 |
| Immunogen: | Homo sapiens (Human) |
| Function | Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression. |
| Protein Name | Kinesin-Like Protein Kif18aMarrow Stromal Kif18aMs-Kif18a |
| Database Links | Reactome: R-HSA-141444Reactome: R-HSA-2132295Reactome: R-HSA-2467813Reactome: R-HSA-2500257Reactome: R-HSA-5663220Reactome: R-HSA-6811434Reactome: R-HSA-68877Reactome: R-HSA-9648025Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionRuffleCytoplasmNucleusCytoskeletonMicrotubule Organizing CenterCentrosome |
| Alternative Protein Names | Kinesin-Like Protein Kif18a proteinMarrow Stromal Kif18a proteinMs-Kif18a proteinKIF18A proteinOK proteinSW-cl.108 protein |
Information sourced from Uniprot.org
