Human IL-7RA/CD127 protein (Recombinant) (C-hFc & His) (STJP002675)

SKU:
STJP002675
£97.50 - £291.50
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1.0 EU/Mu g of the protein by LAL method.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IL7 at 2 Mu g/mL (100 Mu L/well) can bind Recombinant Human IL7R alpha, the EC50 of Recombinant Human IL7R alpha is 48.44 ng/mL.|2.Measured by its binding
Gene Symbol: IL7R
Gene ID: 3575
Uniprot ID: IL7RA_HUMAN
Immunogen Region: Glu21-Gly236
Immunogen: Recombinant Human IL-7RA/CD127 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu21-Gly236) of human IL7R alpha (Accession #NP_002176.2) fused with an Fc, 6×His tag at the C-terminus.
Immunogen Sequence: ESGYAQNGDLEDAELDDYSF SCYSQLEVNGSQHSLTCAFE DPDVNITNLEFEICGALVEV KCLNFRKLQEIYFIETKKFL LIGKSNICVKVGEKSLTCKK IDLTTIVKPEAPFDLSVVYR EGANDFVVTFNTSHLQKKYV KVLMHDVAYRQEKDENKWTH VNLSSTKLTLLQRKLQPAAM YEIKVRSIPDHYFKGFWSEW SPSYYFRTPEINNSSG
Function Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
Protein Name Interleukin-7 Receptor Subunit Alpha
Il-7 Receptor Subunit Alpha
Il-7r Subunit Alpha
Il-7r-Alpha
Il-7ra
Cdw127
Cd Antigen Cd127
Database Links Reactome: R-HSA-1266695
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Membrane
Isoform 4: Secreted
Alternative Protein Names Interleukin-7 Receptor Subunit Alpha protein
Il-7 Receptor Subunit Alpha protein
Il-7r Subunit Alpha protein
Il-7r-Alpha protein
Il-7ra protein
Cdw127 protein
Cd Antigen Cd127 protein
IL7R protein

Information sourced from Uniprot.org