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Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP001843)

Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP001843)

Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP001843)

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STJP001843

£78.50 - £302.50

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human IFN-gamma R2-C-RaFC protein was developed from hek293 cells and has a target region of C-RaFC. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	IFNGR2
Gene ID:	3460
Uniprot ID:	INGR2_HUMAN
Immunogen Region:	Ser28-Asp240
Immunogen:	Recombinant Human IFN-gamma R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser28-Asp240) of human IFN-gamma R2 (Accession #NP_005525.2) fused with and a RaFc tag at the C-terminus.

Function	Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding.
Protein Name	Interferon Gamma Receptor 2 Ifn-Gamma Receptor 2 Ifn-Gamma-R2 Interferon Gamma Receptor Accessory Factor 1 Af-1 Interferon Gamma Receptor Beta-Chain Ifn-Gamma-R-Beta Interferon Gamma Transducer 1
Database Links	Reactome: R-HSA-877300 Reactome: R-HSA-877312 Reactome: R-HSA-9679191 Reactome: R-HSA-9732724
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Cytoplasmic Vesicle Membrane Golgi Apparatus Membrane Endoplasmic Reticulum Membrane Cytoplasm Has Low Cell Surface Expression And High Cytoplasmic Expression In T Cells The Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling
Alternative Protein Names	Interferon Gamma Receptor 2 protein Ifn-Gamma Receptor 2 protein Ifn-Gamma-R2 protein Interferon Gamma Receptor Accessory Factor 1 protein Af-1 protein Interferon Gamma Receptor Beta-Chain protein Ifn-Gamma-R-Beta protein Interferon Gamma Transducer 1 protein IFNGR2 protein IFNGT1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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