| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.065ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This HVCN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
HVCN1 |
| Gene ID: |
84329 |
| Uniprot ID: |
HVCN1_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. |
| Post Translational Modifications | Phosphorylation may enhance channel gating. |
| Function | Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. |
| Protein Name | Voltage-Gated Hydrogen Channel 1Hydrogen Voltage-Gated Channel 1Hv1Voltage Sensor Domain-Only Protein |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1300642Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneDetected Mainly At Intracellular Membranes Upon Overexpression In Hela CellsBut Not In Other Cell Types |
| Alternative ELISA Names | Voltage-Gated Hydrogen Channel 1 ELISA kitHydrogen Voltage-Gated Channel 1 ELISA kitHv1 ELISA kitVoltage Sensor Domain-Only Protein ELISA kitHVCN1 ELISA kitVSOP ELISA kitUNQ578 ELISA kitPRO1140 ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
