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Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP002714)

Human Fc-gamma RI/CD64 protein (Recombinant) (C-His) (STJP002714)

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STJP002714

£357.50 - £567.50

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General Information
Product Properties
Target Information
Additional Info
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Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Fc-gamma RI/CD64-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution PBS, pH 7.4.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FCGR1A
Gene ID:	2209
Uniprot ID:	FCGR1_HUMAN
Immunogen Region:	Met1-Pro288
Immunogen:	Recombinant Human Fc-gamma RI/CD64 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Pro288) of human CD64 (Accession #NP_000557.1) fused with a 6×His tag at the C-terminus.

Post Translational Modifications	Phosphorylated on serine residues.
Function	High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Protein Name	High Affinity Immunoglobulin Gamma Fc Receptor I Igg Fc Receptor I Fc-Gamma Ri Fcri Fc-Gamma Ria Fcgammaria Cd Antigen Cd64
Database Links	Reactome: R-HSA-1236978 Reactome: R-HSA-198933 Reactome: R-HSA-2029481 Reactome: R-HSA-2029482 Reactome: R-HSA-2029485 Reactome: R-HSA-877300 Reactome: R-HSA-9664323
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Stabilized At The Cell Membrane Through Interaction With Fcer1g
Alternative Protein Names	High Affinity Immunoglobulin Gamma Fc Receptor I protein Igg Fc Receptor I protein Fc-Gamma Ri protein Fcri protein Fc-Gamma Ria protein Fcgammaria protein Cd Antigen Cd64 protein FCGR1A protein FCG1 protein FCGR1 protein IGFR1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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