Name: Human ETHE1 protein (Recombinant) (N-His) (STJP010790)
SKU: STJP010790
Availability: InStock

Human ETHE1 protein (Recombinant) (N-His) (STJP010790)

SKU:

STJP010790

£328.50 - £1,437.50

Free Shipping

Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human ETHE1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus.
Protein Name	Persulfide Dioxygenase Ethe1 - Mitochondrial Ethylmalonic Encephalopathy Protein 1 Hepatoma Subtracted Clone One Protein Sulfur Dioxygenase Ethe1
Database Links	Reactome: R-HSA-1614517
Cellular Localisation	Cytoplasm Nucleus Mitochondrion Matrix
Alternative Protein Names	Persulfide Dioxygenase Ethe1 - Mitochondrial protein Ethylmalonic Encephalopathy Protein 1 protein Hepatoma Subtracted Clone One Protein protein Sulfur Dioxygenase Ethe1 protein ETHE1 protein HSCO protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP003644	Human ALDOA protein (Recombinant) (N-His) (STJP003644)	E. coli
STJP003667	Human KRT1 protein (Recombinant) (N-His) (STJP003667)	E. coli
STJP003695	Human ALDH2 protein (Recombinant) (N-His) (STJP003695)	E. coli

Human ETHE1 protein (Recombinant) (N-His) (STJP010790)

General Information