Post Translational Modifications | Hyperglycosylated in carcinoma tissue as compared with autologous normal epithelia. Glycosylation at Asn-198 is crucial for protein stability. |
Function | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
Protein Name | Epithelial Cell Adhesion MoleculeEp-CamAdenocarcinoma-Associated AntigenCell Surface Glycoprotein Trop-1Epithelial Cell Surface AntigenEpithelial GlycoproteinEgpEpithelial Glycoprotein 314Egp314Hegp314Ks 1/4 AntigenKsaMajor Gastrointestinal Tumor-Associated Protein Ga733-2Tumor-Associated Calcium Signal Transducer 1Cd Antigen Cd326 |
Database Links | Reactome: R-HSA-202733 |
Cellular Localisation | Lateral Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionColocalizes With Cldn7 At The Lateral Cell Membrane And Tight Junction |
Alternative Antibody Pair Names | Epithelial Cell Adhesion Molecule antibody pairEp-Cam antibody pairAdenocarcinoma-Associated Antigen antibody pairCell Surface Glycoprotein Trop-1 antibody pairEpithelial Cell Surface Antigen antibody pairEpithelial Glycoprotein antibody pairEgp antibody pairEpithelial Glycoprotein 314 antibody pairEgp314 antibody pairHegp314 antibody pairKs 1/4 Antigen antibody pairKsa antibody pairMajor Gastrointestinal Tumor-Associated Protein Ga733-2 antibody pairTumor-Associated Calcium Signal Transducer 1 antibody pairCd Antigen Cd326 antibody pairEPCAM antibody pairGA733-2 antibody pairM1S2 antibody pairM4S1 antibody pairMIC18 antibody pairTACSTD1 antibody pairTROP1 antibody pair |
Information sourced from Uniprot.org