• Human DTNb (Dystrobrevin Beta) Sandwich ELISA Kit (STJE0008527)

Human DTNb (Dystrobrevin Beta) Sandwich ELISA Kit (STJE0008527)

SKU:
STJE0008527

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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.055ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This DTNb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: DTNB
Gene ID: 1838
Uniprot ID: DTNB_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in brain, kidney and pancreas.
Post Translational Modifications Phosphorylated by PKA. Phosphorylation at Thr-11 alters the interaction with KIF5A.
Function Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids. May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses.
Protein Name Dystrobrevin Beta
Dtn-B
Beta-Dystrobrevin
Database Links
Cellular Localisation Cytoplasm
Postsynaptic Density
Cell Projection
Dendrite
Basal Cell Membrane
Postsynapse
Nucleus
Localized At Inhibitory Synapses On The Dendrites Of Cerebellar Purkinje Cells
Alternative ELISA Names Dystrobrevin Beta ELISA kit
Dtn-B ELISA kit
Beta-Dystrobrevin ELISA kit
DTNB ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance