| Applications: |
ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: |
0.055ng/mL |
| Detection Limit: |
0.156-10ng/mL |
| Short Description: |
This DTNb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: |
4.5 hrs |
| Gene Symbol: |
DTNB |
| Gene ID: |
1838 |
| Uniprot ID: |
DTNB_HUMAN |
| Sample Type: |
tissue homogenates or other biological fluids. |
| Tissue Specificity | Highly expressed in brain, kidney and pancreas. |
| Post Translational Modifications | Phosphorylated by PKA. Phosphorylation at Thr-11 alters the interaction with KIF5A. |
| Function | Scaffolding protein that assembles DMD and SNTA1 molecules to the basal membrane of kidney cells and liver sinusoids. May function as a repressor of the SYN1 promoter through the binding of repressor element-1 (RE-1), in turn regulates SYN1 expression and may be involved in cell proliferation regulation during the early phase of neural differentiation. May be required for proper maturation and function of a subset of inhibitory synapses. |
| Protein Name | Dystrobrevin BetaDtn-BBeta-Dystrobrevin |
| Database Links | |
| Cellular Localisation | CytoplasmPostsynaptic DensityCell ProjectionDendriteBasal Cell MembranePostsynapseNucleusLocalized At Inhibitory Synapses On The Dendrites Of Cerebellar Purkinje Cells |
| Alternative ELISA Names | Dystrobrevin Beta ELISA kitDtn-B ELISA kitBeta-Dystrobrevin ELISA kitDTNB ELISA kit |
| output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
