| Host: |
HEK293 cells |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Human DPEP1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of 20mM PB, 150mM NaCl, pH7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DPEP1 |
| Gene ID: |
1800 |
| Uniprot ID: |
DPEP1_HUMAN |
| Immunogen Region: |
Asp17-Ser385 |
| Immunogen: |
Recombinant Human DPEP1 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Asp17-Ser385) of human Dipeptidase 1 (Accession #P16444) fused with a 6×His tag at the C-terminus. |
| Function | Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. |
| Protein Name | Dipeptidase 1Beta-LactamaseDehydropeptidase-IMicrosomal DipeptidaseRenal DipeptidaseHrdp |
| Database Links | Reactome: R-HSA-2142691Reactome: R-HSA-5423646Reactome: R-HSA-9664535 |
| Cellular Localisation | Apical Cell MembraneLipid-AnchorGpi-AnchorCell ProjectionMicrovillus MembraneBrush Border Membrane |
| Alternative Protein Names | Dipeptidase 1 proteinBeta-Lactamase proteinDehydropeptidase-I proteinMicrosomal Dipeptidase proteinRenal Dipeptidase proteinHrdp proteinDPEP1 proteinMDP proteinRDP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
