Human DPEP1 protein (Recombinant) (C-His) (STJP002701)

SKU:
STJP002701

£110.50 - £286.50
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human DPEP1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DPEP1
Gene ID: 1800
Uniprot ID: DPEP1_HUMAN
Immunogen Region: Asp17-Ser385
Immunogen: Recombinant Human DPEP1 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Asp17-Ser385) of human Dipeptidase 1 (Accession #P16444) fused with a 6×His tag at the C-terminus.
Function Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
Protein Name Dipeptidase 1
Beta-Lactamase
Dehydropeptidase-I
Microsomal Dipeptidase
Renal Dipeptidase
Hrdp
Database Links Reactome: R-HSA-2142691
Reactome: R-HSA-5423646
Reactome: R-HSA-9664535
Cellular Localisation Apical Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Projection
Microvillus Membrane
Brush Border Membrane
Alternative Protein Names Dipeptidase 1 protein
Beta-Lactamase protein
Dehydropeptidase-I protein
Microsomal Dipeptidase protein
Renal Dipeptidase protein
Hrdp protein
DPEP1 protein
MDP protein
RDP protein

Information sourced from Uniprot.org

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